Mulyadi, Mulyadi and Sunnati, Sunnati and Azhary, Mulkan (2016) The Correlation between Pulmonary Function Tests and The Salivary MMP-9 Activity among Chronic Obstructive Pulmonary Disease (COPD) Patients. Procedia Chemistry, 18. pp. 194-198. ISSN 1876-6196
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Abstract
The spirometry test is routinely performed to assess FEV1, FVC, and FEV1/FVC ratio among chronic obstructive pulmonary disease (COPD) patients with the increased activity of MMP-9. Saliva is less invasive to assess the MMP-9 activity. This study aimed to compare Pulmonary Function Tests to estimate the MMP-9 activity. The respondents were 30 COPD outpatients from Pulmonary Policlinic. Results showed mean ratio of FEV1, FVC, FEV1/FVC (SD) and that of the salivary MMP-9 activity were 1.67 (0.12) L, 2.97 (0.43) L, 56.15 (8.43) % and 1.85 (1.54) μM respectively. The correlation between FEV1, FVC, and FEV1/FVC ratio and the salivary MMP-9 activity was insignificant (p>0.05). The pulmonary function tests were not able to estimate the salivary MMP-9 activity. The findings suggest further activities of MMP-9 from other samples for comparison of protease activity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Spirometry, Salivary, MMP-9, Comparison |
| Subjects: | R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine > Program Study of Medicine |
| Depositing User: | Mr. . Bagas |
| Date Deposited: | 14 Jun 2020 11:36 |
| Last Modified: | 11 May 2023 07:37 |
| URI: | http://repository.unusa.ac.id/id/eprint/6100 |
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