Toxicology properties of commercial anti-mosquitos and their effects on carboxyhemoglobin and malondialdehyde levels

Andini, Ary and Sunaryo, Merry and Ayu, Friska and Syafiuddin, Achmad (2022) Toxicology properties of commercial anti-mosquitos and their effects on carboxyhemoglobin and malondialdehyde levels. Environmental Quality Management. ISSN 1520-6483

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Official URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/tq...

Abstract

Exposure of carbon monoxide (CO) released by insect repellent has a negative impact on health by forming carboxyhemoglobin (CO-Hb) as a trigger for oxidative stress in the human body. Therefore, the objective of the study was to investigate the effect of commercial anti-mosquitos on CO-Hb and malondialdehyde (MDA) levels in the blood. Effect of electric spray, coils, and electric mats on CO-Hb and MDA levels in blood was evaluated using male Wistar rats (8 h per day) and monitored for 20 days. The study found that the highest increase in CO-Hb and CO-Hb levels in the blood was observed when exposed to electric spray formula compared to other anti-mosquitos. In addition, the highest increase in MDA levels also occurred when exposed to the electric spray. Statistical analysis revealed that there was a significant relationship between CO-Hb and MDA levels in the blood (p-value = 0.000). High CO-Hb levels in the blood could stimulate oxidative stress and lead to cell damage in the body.

Item Type: Article
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Health > Program Study of Occupational Health and Safety
Depositing User: Mr. . Aji
Date Deposited: 30 Aug 2022 01:01
Last Modified: 30 Aug 2022 01:01
URI: http://repository.unusa.ac.id/id/eprint/8791

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