Putri, Winawati Eka and Widyaswari, Meidyta Sinantryana and Salim, Hotimah Masdan (2020) Proinflammatorycytokines profile On Skin Aging In Jemursari Islamic Hospital. International Journal of Advances in Engineering and Management (IJAEM), 2 (11). pp. 246-249. ISSN 2395-5252
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Abstract
Aging is a complex process and make progressive loss of functional capacity of organ such as skin. There is an imbalance of immune system in skin aging. Proinflammatory cytokines such as IL-6 and TNF-α were elevated in skin aging.Purpose:This study aims to observe about proinflammatory cytokines on skin aging in Jemursari Islamic Hospital. Methods:This research is an observational study with cross sectional design. The IL-6 and TNF-α level was measured by using sandwich ELISA technique. Results: The mean level of IL-6 and TNF-α in subjects aged 56-75 years were 19,99 ng/ml and 2,86 ng/ml, respectively. Those were higher than aged 45-55 years. In males group, IL-6 was more elevated than females group. Meanwhile in females group, TNF-α was more elevated than in males group.The mean level of IL-6 and TNF-α in overweight groups were more elevated than normal BMI groups. Conclusion: Subjects in Jemursari Islamic hospital had elevated IL-6 and TNF-α level.However, there wasneeded a much further research inorder find correlation between skin aging and proinflammatory cytokines.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Skin aging, IL-6, TNF-α |
| Subjects: | R Medicine > RL Dermatology > RL87-94 Care and hygiene |
| Divisions: | Faculty of Medicine > Program Study of Medicine |
| Depositing User: | Mr. . Aji |
| Date Deposited: | 26 Dec 2022 08:15 |
| Last Modified: | 31 Jan 2023 04:39 |
| URI: | http://repository.unusa.ac.id/id/eprint/9125 |
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