Muhsin, M. and Mulyadi, Mulyadi and Fong, M. Y. (2015) The Role of Host lmmunity in Lymphatic Filariasis. Bandung International Scientific Meeting on Parasitology & Tropical Diseases. p. 31. ISSN 791527187-3
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Abstract
Lymphatic filariasis (LF) is a chronic neglected tropical disease and continues to present challenge to current elimination programs. lt is estimated that 1.3 billion people live in endemic areas for LF with 120 million people infected worldwide. There are three species that cause LF in humans: Wuchereria bancrofti, Brugia malayiand B. tinrori. The role of host immunity in reducing inflamnration, number of worms, circulating microfilaria and in preventing disability still leaves a big question mark and requires further research. Both types of human immunity, innate and adaptive immunity, are believed to take an important part in controlling or even worsening the disease. Local and systemic inflammation which involves various cell types and molecules has long been recognized to occur in patients with filariasis, especially in early phases of infection as well as in'the chronic stage. Several cell types are involved in the immune response against filarial infection and are important for worm clearance as well as inducing the pathology. This review discusses some of these cell types and their role in host immunity against filarial infection.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Program Study of Medicine |
| Depositing User: | Mr. . Aji |
| Date Deposited: | 23 Jun 2020 03:11 |
| Last Modified: | 11 May 2023 07:34 |
| URI: | http://repository.unusa.ac.id/id/eprint/6134 |
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