NEUROPROTECTIVE ACTIVITY of EXTRACT of CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY

Putra, Reza Mahendra and ROFIK, AINUL and Salim, Hotimah Masdan and ULFA, MARIA and Awwalia, Evi Sylvia (2021) NEUROPROTECTIVE ACTIVITY of EXTRACT of CELERY (APIUM GRAVEOLENS) IN INSILICO STUDY. Medical and Health Science Journal, 5 (2). pp. 28-31. ISSN 2549-7588

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Abstract

Backround: Celery (Apium graveolens L., Apiaceae) is one of the medicinal plants with secondary metabolite components that have pharmacological effects such as vitamin (choline) content. This study aims to evaluate the mechanism and interaction of choline contained in celery on its effectiveness as a neuroprotective. Methods: This research is an experimental research using the in silico study. Results: The insilico search found that the choline content in celery binds to Slc5a7, Chat and Ache. Which has a function in the process of neurotransmitter biosynthesis, neurotransmitter metabolic processes and neurotransmitter secretion processes Conclusion: The celery (Apium graveolens L., Apiaceae) have pharmacological activity as neuroprotective through the interaction of Slc5a7, Chat and Ache.

Item Type:	Article
Uncontrolled Keywords:	Celery (Apium graveolens), Coline, insilico
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medicine > Program Study of Medicine
Depositing User:	Mr. . Aji
Date Deposited:	21 Oct 2021 04:49
Last Modified:	30 Apr 2024 01:12
URI:	http://repository.unusa.ac.id/id/eprint/6696

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