Handayani, . and Wulandari, Devyana Dyah and Wulansari, Devyani Diah (2022) Phytochemical screening, antioxidant activity and cytotoxicity assay from noni juice and fermented noni (Morinda citrifolia L.). Bali Medical Journal, 11 (3). pp. 1168-1171. ISSN 2302-2914
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Abstract
Introduction: Noni fruit is one of the plants that is often used in traditional medicine as a medicine for high blood pressure, beriberi, smooth urination, inflammation of the gallbladder, colitis, dysentery, constipation, spleen pain, liver disease, diabetes and back pain. This study aimed to analyze the content of bioactive compounds, antioxidant properties and cytotoxic activity of fermented noni juice and noni juice. Method: Identification of the content of bioactive compounds was carried out using Gas Chromatography (GC), antioxidant activity testing using the DPPH method (2,2-Diphenyl-1 picrylhydrazine) and cytotoxic testing using the Brine Shrimp Lethality Test (BSLT) method. Results: The results showed that the content of phenolic compounds contained in noni juice and fermented noni juice had strong antioxidant properties with the IC50 value for noni juice of 22.23 ppm and for fermented noni juice of 13.95 ppm. Meanwhile, the results of the cytotoxic test of noni juice and fermented noni showed that the LC50 values of 33.26 ppm and 2.25 ppm respectively. Conclusion: It can be concluded that both of these materials have high antioxidant activity and potential as anticancer.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Noni, Antioxidant, Sitotoksik, Phenolic, Fermented |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Program Study of Medicine |
| Depositing User: | Mr. . Aji |
| Date Deposited: | 06 Oct 2022 01:07 |
| Last Modified: | 06 Oct 2022 02:24 |
| URI: | http://repository.unusa.ac.id/id/eprint/8923 |
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